Evidence by design
Randomized human trials can test outcomes under specified conditions. Animal and digestion models explore mechanisms and protein quality. Ex-vivo systems examine human-derived microbiota outside the body. Life-cycle assessments model environmental scenarios. None should be mistaken for another.
Effect of Yeast Protein on Muscle Mass and Performance in an Adult Population – a Double Blind, Randomised Controlled Trial
Total and trunk lean mass increased from baseline in both protein groups, with effects particularly apparent among participants with lower habitual protein intake.
Briskey D, Skinner RA, Zhang H, Chen Z, Rao A · 2024 · Journal of Food and Nutrition Research 12(5):292–300
DOI 10.12691/jfnr-12-5-9 ↗The Impact of Oral Whey Protein and Yeast Protein Supplementation for 6 Months on Skeletal Muscle Mass, Strength, and Function in the Elderly
Walking speed and SPPB improved more in supplemented groups than control. Muscle mass and handgrip strength showed no significant between-group differences.
Bai Huijing et al. · 2026 · Food Science & Nutrition 14:e71552
DOI 10.1002/fsn3.71552 ↗Evaluation of the nutritional quality of yeast protein in comparison to animal and plant proteins using growing rats and INFOGEST model
Yeast protein had a strong indispensable-amino-acid profile, but lower measured true protein and ileal amino-acid digestibility than comparison proteins in this experiment.
Cao X, Liu H, Yang M, Mao K, Wang X, Chen Z, Ran M, Hao L · 2025 · Food Chemistry
DOI 10.1016/j.foodchem.2024.141178 ↗